Number of reported cases of tuberculosis (DOTS) (number)
| 2000 | 2005 | 2010 | 2011 | 2012 | 2013 | 2014 | 2015 | 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 |
| Panama | 1,169 | 1,637 | 1,541 | 1,632 | 1,520 | 1,449 | 1,457 | 1,646 | 1,810 | 1,874 | 1,723 | 1,265 | 1,133 | 1,452 | 1,645 | 2,077 |
| Costa Rica | 585 | 534 | 492 | 514 | 475 | 410 | 463 | 424 | 368 | 379 | 401 | 405 | 342 | 350 | 392 | 474 |
| Dominican Republic | 5,291 | 5,003 | 3,964 | 4,309 | 4,262 | 4,450 | 4,405 | 4,504 | 4,235 | 3,851 | 3,857 | 3,588 | 2,619 | 3,374 | 4,080 | 4,377 |
| Nicaragua | 2,402 | 1,907 | 2,448 | 2,693 | 2,790 | 2,742 | 2,632 | 2,465 | 2,339 | 2,255 | 2,109 | 2,248 | 1,886 | 1,836 | 2,102 | 2,122 |
| Guatemala | 2,913 | 3,803 | 3,322 | 3,040 | 3,442 | 3,311 | 3,163 | 3,325 | 3,223 | 3,445 | 3,568 | 3,716 | 2,750 | 3,089 | 4,092 | 4,733 |
| Honduras | 6,406 | 3,333 | 2,876 | 3,233 | 3,014 | 2,981 | 2,789 | 2,906 | 2,886 | 2,798 | 2,838 | 2,424 | 1,847 | 2,063 | 2,297 | 2,616 |
| El Salvador | 1,485 | 1,794 | 1,700 | 1,896 | 2,053 | 2,176 | 2,206 | 2,452 | 3,034 | 3,666 | 3,615 | 3,009 | 2,042 | 1,936 | 2,531 | 4,265 |
| Belize | 106 | 102 | 145 | 74 | 84 | 121 | 72 | 78 | 120 | 117 | 99 | 91 | 78 | 72 | 75 | 81 |