Patent applications are worldwide patent applications filed through the Patent Cooperation Treaty procedure or with a national patent office.
| 1990 | 2000 | 2005 | 2010 | 2011 | 2012 | 2013 | 2014 | 2015 | 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Antigua and Barbuda | 5 | ||||||||||||||
| Bolivia | 9 | 12 | 59 | 8 | 5 | ||||||||||
| Cuba | 105 | 62 | 38 | 27 | 24 | 32 | 29 | 29 | 27 | 33 | 21 | ||||
| Ecuador | 10 | 11 | 4 | 7 | 24 | 20 | 45 | 16 | 34 | 29 | 33 | 35 | |||
| Nicaragua | 14 | 2 | 4 | 3 | 1 | ||||||||||
| Saint Lucia | 5 | 3 | 2 | ||||||||||||
| Venezuela (Bolivarian Republic of) | 262 | 56 | 121 | 70 | 61 | 65 | 74 | 55 | 47 | 35 | 96 |